Research status of neurogenic supine hypertension

doi:10.3969/j.issn.1672-6731.2020.11.014

Abstract

Abstract:

Neurogenic supine hypertensive (NSH) is one of the types of autonomic nervous function failure, often occurs in neurogenic orthostatic hypotension (NOH) patients. The exact pathogenesis is unknown and may be related to the dysfunction of the stress-reflex buffering function. NSH lacks specificity. The current diagnostic criteria are systolic blood pressure ≥ 140 mm Hg and/or diastolic blood pressure ≥ 90 mm Hg measured after at least 5 min of supine rest in diagnosed NOH patients. Patients with elevated blood pressure at night or during sleep should consider the possibility of NSH. Treatment requires both NOH and NSH, and there is currently a lack of effective drugs to treat NSH.

Key words: Hypertension, Posture, Autonomic pathways, Review

摘要：

神经源性仰卧位高血压是自主神经功能衰竭的一种表现，常与神经源性直立性低血压伴随存在，其确切发病机制尚不清楚，可能与动脉压力反射缓冲功能障碍有关。神经源性仰卧位高血压缺乏特征性临床表现，目前的诊断标准是，诊断明确的神经源性直立性低血压患者仰卧位休息至少5分钟后测量血压，收缩压≥ 140 mm Hg/舒张压≥ 90 mm Hg；夜间或睡眠时血压升高的患者应考虑神经源性仰卧位高血压可能。治疗原则需兼顾神经源性仰卧位高血压和神经源性直立性低血压，目前尚缺乏有效治疗药物。

关键词: 高血压, 体位, 自主神经通路, 综述

DING Yan, YUAN Yuan, LI Ning, ZHAN Shu-qin. Research status of neurogenic supine hypertension[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2020, 20(11): 1014-1019.

丁岩, 袁媛, 李宁, 詹淑琴. 神经源性仰卧位高血压研究现状[J]. 中国现代神经疾病杂志, 2020, 20(11): 1014-1019.

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