Abstract:

Neurosyphilis refers to a chronic infectious disease caused by Treponema pallidum (TP) infection of the central nervous system. The clinical manifestations of neurosyphilis are varied, and the misdiagnosis rate is very high. Particularly when combined with HIV infection, clinical manifestations and laboratory examination of neurosyphilis become more complicated. Currently, there is still no gold standard for the diagnosis of neurosyphilis. Clinical manifestations, laboratory examination, imaging examination and other aspects should be included in the comprehensine analysis of neurosyphilis. Penicillin is still the first choice for the treatment of neurosyphilis. This paper reviews the research progress on the diagnosis and treatment of neurosyphilis, so as to strengthen the understanding of neurosyphilis.

Key words: Neurosyphilis, Review

摘要：

神经梅毒系指梅毒螺旋体感染中枢神经系统导致的慢性传染性疾病。神经梅毒临床表现多样，误诊率极高，特别合并人类免疫缺陷病毒感染时，神经梅毒的临床表现和实验室结果更加复杂。神经梅毒迄今仍无诊断“金标准”，需结合临床表现、实验室检查、影像学检查等多方面进行综合判断。青霉素是治疗神经梅毒的首选药物。本文拟就神经梅毒的诊断与治疗新进展进行简要概述，以提高临床医师对神经梅毒的认识。

关键词: 神经梅毒, 综述