Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2014, Vol. 14 ›› Issue (10): 858-860. doi: 10.3969/j.issn.1672-6731.2014.10.006

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Research progress in immunological mechanism of delayed encephalopathy after acute carbon monoxide poisoning

FENG Kai1, ZHENG Zhi-dong1, XU Xian-hao2   

  1. 1Department of Neurology, Beijing Shunyi Hospital, Beijing 101300, China
    2Department of Neurology, Beijing Hospital, Beijing 100730, China
  • Online:2014-10-25 Published:2014-10-14
  • Contact: FENG Kai (Email: fk168@126.com)

一氧化碳中毒迟发性脑病免疫学机制研究进展

冯凯, 郑志东, 许贤豪   

  1. 作者单位:101300 北京市顺义区医院神经内科(冯凯,郑志东);100730 卫生部北京医院神经内科(许贤豪)
  • 通讯作者: 冯凯 (Email:fk168@126.com)

Abstract: Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is a syndrome constituted by acute dementia, psychiatric symptoms, pyramidal and extrapyramidal symptoms, which can be developed after the original clinical symptoms of carbon monoxide poisoning recovered. Lots of studies have been done to explain the mechanisms of DEACMP, and more and more researches have demonstrated that the immunological mechanism may be involved in or play an important role on the pathogenesis of the process. This article will review the researches of immunological mechanism of DEACMP in recent years and give some prompts to clinical study in the future.

Key words: Carbon monoxide poisoning, Brain diseases, Review

摘要: 一氧化碳中毒迟发性脑病系指部分一氧化碳中毒患者在急性中毒症状恢复后再次出现一系列以急性痴呆、精神症状,以及锥体束和锥体外系症状为主的神经系统症状与体征。目前对其发病机制尚不明确,越来越多的研究显示免疫学机制可能参与其发病并起重要作用。本文拟对近年一氧化碳中毒迟发性脑病免疫学机制的研究进展进行概述,以期对今后临床研究有所提示。

关键词: 一氧化碳中毒, 脑疾病, 综述