Abstract: microRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs, which regulate gene expression by binding messenger RNA (mRNA). Thyroid cancer is the most common endocrine cancer. Papillary thyroid carcinoma (PTC) is a common type of thyroid cancer, and its incidence has increased dramatically worldwide. Recent evidence suggests that miRNAs play an important role in thyroid carcinogenesis, development and prognosis, especially in PTC.

Key words: miRNA, Papillary thyroid carcinoma, Signaling pathway