Abstract: There is a interaction between long con-coding RNA(lncRNA) and microRNA(miRNA). lncRNA can interact with the miRNA as a competing endogenous RNA(ceRNA) to participate in the expression regulation of target genes. Whereas miRNA can regulate lncRNA to exert biological functions by RNA-inducde silencing complex(RISC). The interaction between lncRNA and miRNA participates in the occurrence of various diseases together. Now this paper summarizes the influence of interaction between lncRNA and miRNA on disease.

Key words: lncRNA, microRNA, interactions, diseases