Abstract: Given limits of traditional medical and surgical treatments in the progress of Parkinson’s disease, the therapeutic strategy of cell transplantation to replace with loss dopamine neurons has received more attention gradually. Many researches have domenstrated stem cells could be induced into dopamine neurons in vitro through different methods. Here, recent data and findings are reviewed. By evaluation, better methods and cell sources could be found and further investigated in future, which may facilitate translation of stem cell transplantation techniques into a clinical treatment for Parkinson’s disease.

Key words: stem cell, dopamine neurons, induction, in vitro