基础医学与临床 ›› 2010, Vol. 30 ›› Issue (12): 1338-1341.

• 短篇综述 • 上一篇    下一篇

侵袭性念珠菌病实验室诊断现状的分析与思考

胡冬梅,车小燕   

  1. 南方医科大学附属珠江医院
  • 收稿日期:2009-09-23 修回日期:2009-12-15 出版日期:2010-12-05 发布日期:2010-12-05
  • 通讯作者: 车小燕

Analysis and Reflection Of Current Laboratory Diagnosis on Invasive Candidiasis

HU Dong-mei ,CHE Xiao-yan   

  1. Zhujiang Hospital, Southern Medical University
  • Received:2009-09-23 Revised:2009-12-15 Online:2010-12-05 Published:2010-12-05
  • Contact: CHE Xiao-yan

摘要: 侵袭性念珠菌病是第四位医院血源感染性疾病,迄今缺乏理想的诊断方法。尽管以念珠菌抗原、抗体和核酸为靶标的检测方法的研究取得了很大的进展,但由于敏感性、特异性、标准化以及实验设计等原因,难以解决临床实际问题。高度保守、含量丰富的诊断标志物可能是解决这一问题的良好出路。

关键词: 侵袭性念珠菌病, 诊断

Abstract: Ideal diagnostic methods of invasive candidiasis, the fourth nosocomial infection are urgently desirable to date. Even though great progress has been made on the subject which uses the antigen, antibody and nucleotide as the detection targets, they are hard to solve the practical problems confronted to clinical requirement due to issues such as sensitivity, specificity, standardization and design of study et al. Highly conserved and rich diagnostic markers might be a good solution to such problem.

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