关键词: 纤维瘤病, 硬纤维瘤, 复发, 手术

Abstract: Objective To study the factors influencing the recurrence of aggressive fibromatosis(AF) patients Methods Analyze clinical features and find out factors affecting AF recurrence with univariate and multivariate analysis Results 103 pathologically diagnosed AF patients in which 67 are females were analyzed. Diameter of all the masses was 7.84±5.62cm. 98.2% of all patients received surgery and radical resection rate is 79.4%. First recurrent time after surgery of male and female is 1563±377 and 2117±3704 days respectively, it's 2723±461、657±262、2090±499、812±220、721±234 days for that of abdomen wall、head and neck(H&N), deep mass, joints and chest wall. Recurrent time is 2232±271 and 1347±267 days for those with and without locally surgery history patients. Univariate analysis reveal that gender, tumor site and surgery history of tumor site are prognostic factors of tumor recurrence. Multivariate analysis suggest that only surgery history of tumor site is an independant prognostic factors of AF recurrence after surgery. Conclusion Gender, tumor location and surgery history of tumor site can predict postsurgery recurrence of AF.

Key words: aggressive fibromatosis, desmoid, recurrence, surgery