骨质疏松症合并常见老年综合征的研究进展

doi:10.16352/j.issn.1001-6325.2025.01.0112

基础医学与临床 ›› 2025, Vol. 45 ›› Issue (1): 112-115.doi: 10.16352/j.issn.1001-6325.2025.01.0112

骨质疏松症合并常见老年综合征的研究进展

李淼¹, 李蕊¹, 程新春^2*

1.新疆医科大学研究生学院,新疆乌鲁木齐 830001;
2.新疆维吾尔自治区人民医院老年医学中心,新疆乌鲁木齐 830001

收稿日期:2024-05-13 修回日期:2024-07-15 出版日期:2025-01-05 发布日期:2024-12-25
通讯作者: ^*2272871234@qq.com
基金资助:
新疆维吾尔自治区自然科学基金(2022D01C635)

Research progress on osteoporosis with common geriatric syndromes

LI Miao¹, LI Rui¹, CHENG Xinchun^2*

1. Graduate School of Xinjiang Medical University, Urumqi 830001;
2. Geriatrics Center, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001,China

Received:2024-05-13 Revised:2024-07-15 Online:2025-01-05 Published:2024-12-25
Contact: ^*2272871234@qq.com

摘要/Abstract

摘要： 骨质疏松症(OP)在老年人群中较为常见,老年骨质疏松症患者发生跌倒和骨折的风险与老年综合征密切相关。本文介绍骨质疏松症与老年综合征并存的现状,这些将限制患者的功能独立性,导致更复杂的医疗管理。骨质疏松症与常见老年综合征之间存在某种联系,骨质疏松症患者更易患有更多的老年综合征,生活质量及预后更差。本文对骨质疏松症合并老年综合征的流行病学现状、影响因素及管理策略进行综述,旨在为骨质疏松症的整体化管理提供依据。

关键词: 骨质疏松症, 老年综合征, 健康管理与治疗

Abstract: Osteoporosis is common in elderly population. The risk of falls and bone fractures in elderly patients with osteoporosis are closely related to the elderly syndrome^[1]. This article introduces the coexistence of osteoporosis and geriatric syndrome, which will limit the functional independence of patients and lead to more complex medical management. Osteoporosis has some association with common geriatric syndromes, and patients with osteoporosis are more likely to suffer from more geriatric syndromes, and their quality of life and prognosis are worse. This article reviews epidemiological status, influencing factors and management strategies of osteoporosis comorbid with geriatric syndrome, aiming to provide a basis for the integrated management of osteoporosis.

Key words: osteoporosis, geriatric syndrome, health management and treatment

中图分类号:

R592

李淼, 李蕊, 程新春. 骨质疏松症合并常见老年综合征的研究进展[J]. 基础医学与临床, 2025, 45(1): 112-115.

LI Miao, LI Rui, CHENG Xinchun. Research progress on osteoporosis with common geriatric syndromes[J]. Basic & Clinical Medicine, 2025, 45(1): 112-115.

参考文献

[1] 童玉芬. 中国人口的最新动态与趋势——结合第七次全国人口普查数据的分析[J]. 中国劳动关系学院学报, 2021, 35: 15-25.
[2] Khovasova NO, Naumov AV, Tkacheva ON, et al. Characteristics of geriatric and somatic status in patients with osteoporosis[J]. Probl Endokrinol (Mosk), 2021, 67: 45-54.
[3] 《中国老年骨质疏松症诊疗指南(2023)》工作组, 中国老年学和老年医学学会骨质疏松分会, 中国医疗保健国际交流促进会骨质疏松病学分会,等. 中国老年骨质疏松症诊疗指南(2023)[J]. 中华骨与关节外科杂志, 2023, 16: 865-885.
[4] Tai TW, Li CC, Huang CF, et al. Treatment of osteoporosis after hip fracture is associated with lower all-cause mortality: a nationwide population study[J]. Bone, 2022, 154: 116-216.
[5] 刘婷婷,陈豪,樊建玲,等. 骨质疏松症特殊人群的健康管理及综合治疗进展[J]. 健康体检与管理, 2024, 5: 50-58.
[6] Si L, Winzenberg TM, Jiang Q, et al. Projection of osteoporosis-related fractures and costs in China: 2010-2050[J]. Osteoporos Int, 2015, 26: 1929-1937.
[7] Won CW, Yoo HJ, Yu SH, et al. Lists of geriatric syndromes in the Asian-Pacific geriatric societies[J]. European Geriatric Medicine, 2013, 4: 335-338.
[8] 吴京凤,王新芳,杨伏肖,等. 住院患者老年综合征发生情况及评估分析[J]. 中国实用医药, 2022, 17: 163-165.
[9] Imagama S, Ando K, Kobayashi K, et al. Musculo-skeletal factors and geriatric syndromes related to the absence of musculoskeletal degenerative disease in elderly people aged over 70 years[J]. Biomed Res Int, 2019, 2019: 7097652. doi: 10.1155/2019/7097652.
[10] Dudinskaya EN, Vorobyeva NM, Onuchina JS, et al. The association of osteoporosis and geriatric syndromes in the elderly: data from the russian epidemiological study EVKALIPT[J]. Arch Osteoporos, 2023, 18: 30.doi:0.1007/s11657-023-01217-x.
[11] Liu C, Liu N, Xia Y, et al. Osteoporosis and sarcopenia-related traits: a bi-directional mendelian randomization study[J]. Frontiers in Endocrinology, 2022, 13: 975647. doi: 10.3389/fendo.2022.975647.
[12] 苏晓川,郭智萍,郭清,等. 肌少症与骨质疏松症相关性研究的可视化分析[J]. 中医研究, 2024, 37: 75-82.
[13] Lin YA, Chen LH, Chen FP, et al. The effectiveness of a group kickboxing training program on sarcopenia and osteoporosis parameters in community-dwelling adults aged 50-85 Years[J]. Frontiers in Medicine, 2022,9:815342.doi:10.3389/fmed.2022.815342.
[14] Massari MC, Bimonte VM, Falcioni L, et al. Nutritional and physical activity issues in frailty syndrome during the COVID-19 pandemic[J]. Ther Adv Musculoskelet Dis,2023,15:1759720X231152648.doi:10.1177/1759720X231152648.
[15] Inoue T, Maeda K, Satake S, et al. Osteosarcopenia, the co-existence of osteoporosis and sarcopenia, is associated with social frailty in older adults[J]. Aging Clin Exp Res, 2022, 34: 535-543.
[16] Lima BR, Nunes BKG, Guimarães L, et al. Incidence of delirium following hospitalization of elderly people with fractures: risk factors and mortality[J]. Rev Esc Enferm USP, 2021, 55:e20200467. doi: 10.1590/1980-220X-REEUSP-2020-0467.
[17] Ebrahimpur M, Sharifi F, Shadman Z, et al. Osteoporosis and cognitive impairment interwoven warning signs: community-based study on older adults-Bushehr Elderly Health (BEH) program[J]. Arch Osteoporos, 2020, 15: 140. doi: 10.1007/s11657-020-00817-1.
[18] Kashfi SS, Abdollahi G, Hassanzadeh J, et al. The relationship between osteoporosis and depression[J]. Sci Rep, 2022, 12:11177. doi: 10.1038/s41598-022-15248-w.
[19] Chen K, Wang T, Tong X, et al. Osteoporosis is associa-ted with depression among older adults: a nationwide population-based study in the USA from 2005 to 2020[J]. Public Health, 2024, 226: 27-31.
[20] He B, Lyu Q, Yin L, et al. Depression and osteoporosis: a mendelian randomization study[J]. Calcif Tissue Int, 2021, 109: 675-684.
[21] Genest F, Rak D, Bätz E, et al. Sarcopenia and malnutrition screening in female osteoporosis patients:a cross-sectional study[J]. J Clin Med, 2021, 10:doi: 10.3390/jcm10112344.
[22] Taylor MK, Swerdlow RH, Sullivan DK. Dietary neuroketotherapeutics for alzheimer′s disease: an evidence update and the potential role for diet quality[J]. Nutrients,2019,11:doi:10.3390/nu11081910.
[23] Shams-White MM, Chung M, Du M, et al. Dietary protein and bone health: a systematic review and Meta-analysis from the national osteoporosis foundation[J]. Am J Clin Nutr, 2017, 105: 1528-1543.
[24] 张玉,游如旭,张聪. 骨质疏松症治疗药物合理应用专家共识(2023)[J]. 中国医院药学杂志, 2024,44:985-1006.
[25] Candow DG, Forbes SC, Kirk B, et al. Current evidence and possible future applications of creatine supplementa-tion for older adults[J]. Nutrients, 2021, 13:doi: 10.3390/nu13030745.

骨质疏松症合并常见老年综合征的研究进展

Research progress on osteoporosis with common geriatric syndromes

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 8

编辑推荐

Metrics

本文评价

[1]	戴靖榕, 李婕, 何旭, 李杨, 李燕. 云南省某医院老年医学科住院患者认知功能障碍的患病率及影响因素分析[J]. 基础医学与临床, 2023, 43(3): 468-475.
[2]	杨孟迪, 丁雨露, 王玉洁, 何风英, 孙琳楠, 甄东户. MicroRNA在糖尿病性骨质疏松症中作用的研究进展[J]. 基础医学与临床, 2023, 43(2): 311-316.
[3]	赵晓琦, 董鑫, 刘聪, 任鹏程, 张亮. 丙泊酚促进绝经后骨质疏松大鼠血管生成[J]. 基础医学与临床, 2023, 43(10): 1530-1536.
[4]	阮锋, 李贺伟, 龚艳琳, 刘佳丽, 刘平. 过表达miR-217调控EZH2促进骨质疏松模型小鼠BM-MSCs成骨分化[J]. 基础医学与临床, 2022, 42(9): 1406-1413.
[5]	蒲超, 张珊珊, 吴青霞, 罗栩伟, 王亮, 张波. Lnc000727促进人骨髓间充质干细胞向成骨细胞分化[J]. 基础医学与临床, 2022, 42(7): 1047-1052.
[6]	邱奕雁, 郑羽晨, 郭伟壮, 周文钰, 颜滨, 杨欣建. 共转录因子CITED1在小鼠骨代谢中的调控作用[J]. 基础医学与临床, 2020, 40(3): 294-298.
[7]	李海. 葛根素等减轻去卵巢和铅中毒大鼠骨质疏松症[J]. 基础医学与临床, 2012, 32(7): 831-832.
[8]	李梅邢小平夏维波胡莹莹王鸥姜艳刘怀成孟迅吾. 伊班膦酸钠间断静脉输注治疗北京绝经后骨质疏松症的疗效[J]. 基础医学与临床, 2009, 29(8): 867-871.