基础医学与临床 ›› 2017, Vol. 37 ›› Issue (10): 1478-1481.

• 短篇综述 • 上一篇    下一篇

细胞自噬在血管新生中作用的研究进展

何泉,蒙家泉,刘启华,陈永斌   

  1. 广西医科大学第一附属医院
  • 收稿日期:2016-09-12 修回日期:2016-11-24 出版日期:2017-10-05 发布日期:2017-09-25
  • 通讯作者: 陈永斌 E-mail:651850781@qq.com
  • 基金资助:
    基于内质网应激-自噬探讨龙蛭汤促进缺血性脑损伤大鼠血管新生作用

Research progress of the autophagy role in angiogenesis

  • Received:2016-09-12 Revised:2016-11-24 Online:2017-10-05 Published:2017-09-25
  • Supported by:
    To research the mechanism of longzhi Decoction promoting ischemic brain injury rat angiogenesis on the basis of endoplasmic reticulum stress-autophagy

摘要: 自噬(autophagy)是细胞利用溶酶体降解自身受损的细胞器和大分子物质的过程,在稳定细胞内环境中发挥着重要作用。在血管新生的病理生理过程中,细胞自噬作用持续存在。从自噬的角度探索血管新生的发生发展进程,能够为临床治疗血管相关疾病提供新的思路。

关键词: 自噬, 血管新生, 血管壁细胞

Abstract: The autophagy is a process of cell survival by using the damaged organelles of lysosomal degradation and macromolecular material. It plays an important role in stable environment. The autophagy of cells is persisted in the pathophysiology of angiogenesis. However,To explore the development of the angiogenesis based on autophagy,is the clinical treatment ideas of the vascular disease.

Key words: Autophagy, Angiogenesis, Vessel wall cells