基础医学与临床 ›› 2018, Vol. 38 ›› Issue (3): 405-408.
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王天琪1,苑丽华1,撒元红1,姜华颖1,肖继梅1,孙振高2
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摘要： 抗苗勒氏管激素（AMH）又称苗勒管抑制物质，为转化系统成员。在男性，AMH由未成熟的支持细胞分泌，促进男性胎儿苗勒管（Müllerian）管的退化，并参与睾丸发育和精子发生过程。AMH可影响促性腺激素释放激素(GnRH) 、体分泌的卵泡刺激素(FSH)、黄体生成素(LH)及睾丸间质细胞分泌的睾酮(T) 和抑制素B，从而通过影响下丘脑-垂体-性腺轴（HPG轴）引起男性生殖内分泌相关疾病。
关键词: 关键词: AMH, HPG轴, 生精障碍, 精子发生
Abstract: Anti-Müllerian tube (AMH) hormone, also known as Müllerian inhibitory substances, is a member of the transformation system. In men, AMH, is secreted by immature Sertoli cell, promotes the degradation of male fetal Müllerian tubes, and participates in testicular development and spermatogenesis. AMH can affect gonadotropin-releasing hormone (GnRH), pituitary secretion of follicle stimulating hormone (FSH), luteinizing hormone (LH) and testicular stromal cells secrete testosterone (T), inhibin B, and thus by affecting the hypothalamus- pituitary - gonadal axis (HPG axis) causes male reproductive endocrine related diseases.
Key words: Key words: AMH, HPG axis, Spermatogenesis disturbance, Spermatogenesis
王天琪 苑丽华 撒元红 姜华颖 肖继梅 孙振高. 抗苗勒氏管激素与男性生殖内分泌相关疾病研究进展[J]. 基础医学与临床, 2018, 38(3): 405-408.
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链接本文: https://journal11.magtechjournal.com/Jwk_jcyxylc/CN/
https://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2018/V38/I3/405
