胃癌网膜转移机制的研究进展

doi:10.16352/j.issn.1001-6325.2026.02.0282

基础医学与临床 ›› 2026, Vol. 46 ›› Issue (2): 282-287.doi: 10.16352/j.issn.1001-6325.2026.02.0282

胃癌网膜转移机制的研究进展

隆方文¹, 郑侠^1,2, 钱军^1,2, 章宜芬^3*

1.南京中医药大学附属医院肿瘤科,江苏南京 210004;
2.南京中医药大学江苏省中医药防治肿瘤协同创新中心,江苏南京 210004;
3.南京中医药大学附属医院病理科,江苏南京 210004

收稿日期:2025-01-24 修回日期:2025-05-27 出版日期:2026-02-05 发布日期:2026-01-21
通讯作者: ^* yifen2001@126.com
基金资助:
江苏省中医药管理局(MS2023014)

Research progress on the mechanisms of omental metastasis in gastric cancer

LONG Fangwen¹, ZHENG Xia^1,2, QIAN Jun^1,2, ZHANG Yifen^3*

1. Department of Oncology, the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210004;
2. Jiangsu Collaborative lnnovation Center of Traditional Chinese Medicine in Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing 210004;
3. Department of Pathology, the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210004, China

Received:2025-01-24 Revised:2025-05-27 Online:2026-02-05 Published:2026-01-21
Contact: ^* yifen2001@126.com

摘要/Abstract

摘要： 网膜转移被认为是进展期胃癌中最常见的转移途径之一,同时也是导致晚期胃癌患者预后不良的关键因素,关于胃癌网膜转移的机制,国内外研究已广泛聚焦于多个层面,主要包括肿瘤微环境、基因、黏附分子、外泌体、钙网蛋白、补体等。而这些因素都是在游离的癌细胞在腹腔内定植基础上产生作用的,本文回顾了近年来关于胃癌网膜转移相关机制的国内外研究进展,并分析了其潜在的研究价值与应用前景。

关键词: 胃癌, 网膜转移, 机制研究

Abstract: Omental metastasis is recognized as one of the most common pathways of metastasis in advanced gastric cancer and is also a key factor contributing to poor prognosis in patients with advanced gastric cancer. Research has extensively focused on various aspects concerning the mechanisms of gastric cancer omental metastasis, including the tumor microenvironment, genes, adhesion molecules, exosomes, calreticulin, and complement. These factors act on the basis of the implantation of free cancer cells in the abdominal cavity. This article reviews recent advances in understanding the mechanisms of gastric cancer omental metastasis and discusses their potential research and clinical implications.

Key words: gastric cancer, omental metastasis, mechanism research

中图分类号:

R735.2

隆方文, 郑侠, 钱军, 章宜芬. 胃癌网膜转移机制的研究进展[J]. 基础医学与临床, 2026, 46(2): 282-287.

LONG Fangwen, ZHENG Xia, QIAN Jun, ZHANG Yifen. Research progress on the mechanisms of omental metastasis in gastric cancer[J]. Basic & Clinical Medicine, 2026, 46(2): 282-287.

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胃癌网膜转移机制的研究进展

Research progress on the mechanisms of omental metastasis in gastric cancer

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