Abstract: This paper aims to investigate the predictive value of initial intracranial pressure (ICP) for the prognosis of patients with traumatic brain injury (TBI). A prospective observational study was conducted in 118 TBI patients with ICP monitoring. The initial ICP [receiver operating characteristic (ROC) area = 0.725; 95%CI: 0.635-0.815] was similar to admission Glasgow Coma Scale (GCS; ROC area = 0.716; 95% CI: 0.616-0.816) or Marshall classification (ROC area = 0.690; 95% CI: 0.593-0.787) in predicting the prognosis of TBI patients. A Logistic regression analysis showed that initial ICP was associated with poor prognosis in TBI patients (OR = 0.943, 95%CI: 0.899-0.988; P = 0.014). The initial ICP in TBI patients could be used as an independent predictor of TBI patients' outcomes.

Key words: Intracranial pressure, Craniocerebral trauma, Prognosis

摘要： 共118 例颅脑创伤患者通过颅内压监测，评价颅内压初始值作为判断预后指标的临床预测价值。结果显示，颅内压初始值［受试者工作特征（ROC）曲线下面积为0.725；95%CI：0.635 ~ 0.815］与患者入院时Glasgow 昏迷量表评分（ROC 曲线下面积为0.716；95%CI：0.616 ~ 0.816）和Marshall 分级（ROC 曲线下面积为0.690；95%CI：0.593 ~ 0.787）等项指标具有相似的预后预测价值；经Logistic 回归分析，颅内压初始值与不良预后相关（OR = 0.943，95%CI：0.899 ~ 0.988；P = 0.014）。提示颅内压初始值可以作为颅脑创伤患者不良预后的独立预测因素。

关键词: 颅内压, 颅脑损伤, 预后