Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2013, Vol. 13 ›› Issue (2): 98-101. doi: 10.3969/j.issn.1672-6731.2013.02.003

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The application values of cerebrospinal fluid cytological examination by slide centrifugation for diagnosis of central nervous system infectious diseases

SU Xiu-chu, ZHAO Gang, YANG Yi-ning, DAI Wen, LIU Ting-ting   

  1. Department of Neurology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, Shanxi, China
  • Online:2013-02-25 Published:2013-02-20
  • Contact: SU Xiu-chu (Email: suxiuchu@fmmu.edu.cn)

玻片离心沉淀法脑脊液细胞学检查在中枢神经系统感染性疾病诊断中的应用价值

粟秀初,赵钢,杨毅宁,戴文,刘婷婷   

  1. 710032 西安,第四军医大学西京医院神经内科
  • 通讯作者: 粟秀初(Email:suxiuchu@fmmu.edu.cn)

Abstract: According to the analysis of cerebrospnial fluid (CSF) cytological examination (by slide centrifugation) results of 15 940 central nervous system infectious cases, this cytologic examination method shows definite diagnostic values as follows: 1) better etiological diagnostic value for central nervous system infectious diseases, such as purulent, viral, tuberculous, fungus and parasitic encephalitis meningitis and meningoencephalitis; 2) better differential diagnostic value for acute infectious toxic encephalopathy, meningeal carcinomatosis and central nervous system non-infectious diseases such as tumorous, leukemic and hemorrhagic meningoencephalitis and encephalopathy; 3) better clinical value for severity monitoring and prognostic judgement of central nervous system infectious diseases.

Key words: Central nervous system infections, Cerebrospinal fluid, Cytological techniques, Centrifugation, Precipitation, Review

摘要: 采用微型脑脊液细胞玻片离心沉淀仪和脑脊液细胞学检查方法,对经临床明确诊断为中枢神经系统感染性疾病的15940 例患者的检查结果进行分析,提示该项检查方法对化脓性、病毒性、结核性、真菌性和寄生虫性等中枢神经系统感染性脑炎、脑膜炎和脑膜脑炎具有较好的病因诊断价值;并对急性感染性中毒性脑病、脑膜癌病,肿瘤性、白血病性和出血性等中枢神经系统非感染性脑膜脑炎和脑病具有较好的鉴别诊断价值;而对中枢神经系统感染性脑膜脑炎等疾病的病情监测和预后评价具有良好的临床应用价值。

关键词: 中枢神经系统感染, 脑脊髓液, 细胞学技术, 离心法, 沉淀, 综述