脑功能成像技术在帕金森病步态障碍中的应用进展

doi:10.3969/j.issn.1672-6731.2020.12.013

中国现代神经疾病杂志 ›› 2020, Vol. 20 ›› Issue (12): 1104-1108. doi: 10.3969/j.issn.1672-6731.2020.12.013

2 脑功能成像技术在帕金森病步态障碍中的应用进展

朱志中¹, 于洋¹, 于宁波², 巫嘉陵¹

1 300350 天津市环湖医院康复医学科;
2 300350 天津, 南开大学人工智能学院

收稿日期:2020-12-08 出版日期:2020-12-25 发布日期:2020-12-31
通讯作者: 巫嘉陵,Email:wywjl2009@hotmail.com;于宁波,Email:nyu@nankai.edu.cn
基金资助:
国家自然科学联合基金资助项目（项目编号：U1913208）；国家自然科学基金资助项目（项目编号：61873135）

Research progress of functional brain-neuroimaging technology in Parkinson's disease with gait disorder

ZHU Zhi-zhong¹, YU Yang¹, YU Ning-bo², WU Jia-ling¹

1 Department of Rehabilitation Medicine, Tianjin Huanhu Hospital, Tianjin 300350, China;
2 Collage of Artificial Intelligence, Nankai University, Tianjin 300350, China

Received:2020-12-08 Online:2020-12-25 Published:2020-12-31
Supported by:
This study was supported by the National Natural Science Union Foundation of China (No. U1913208) and the National Natural Science Foundation of China (No. 61873135).

摘要/Abstract

摘要：

步态障碍贯穿于帕金森病疾病全过程，是导致患者失能的主要原因之一，严重影响患者生活质量。帕金森病步态障碍机制复杂，脑功能成像技术可用于分析帕金森病步态障碍相关脑功能变化特点及规律，对于揭示步态障碍的神经病理生理学机制、指导治疗、评估疗效具有重要临床意义。本文对近年来基于fMRI和功能性近红外光谱成像技术在帕金森病步态障碍中的研究进展进行简要概述，以为未来研究提供参考。

关键词: 帕金森病, 步态障碍, 神经性, 磁共振成像, 谱学, 近红外线, 综述

Abstract:

Gait disorder appears in the whole process of Parkinson's disease (PD), which causes disability and serious affects in PD patients. The mechanism of gait disorder in PD is still unclear. Functional brain-neuroimaging can be used to analyse the characteristics and rules of brain functional activity related to gait disorder in PD, and has important clinical significance in revealing the neural physiopathologia mechanism of gait disorder, guiding the treatment and evaluating the curative effect. This paper briefly summarizes the research progress of fMRI and functional near-infrared spectroscopy (fNIRS) in gait disorder of PD, to provide reference for future research.

Key words: Parkinson disease, Gait disorder, neurologic, Magnetic resonance imaging, Spectroscopy, near-infrared, Review

朱志中, 于洋, 于宁波, 巫嘉陵. 脑功能成像技术在帕金森病步态障碍中的应用进展[J]. 中国现代神经疾病杂志, 2020, 20(12): 1104-1108.

ZHU Zhi-zhong, YU Yang, YU Ning-bo, WU Jia-ling. Research progress of functional brain-neuroimaging technology in Parkinson's disease with gait disorder[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2020, 20(12): 1104-1108.

http://journal11.magtechjournal.com/cjcnn/CN/Y2020/V20/I12/1104

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