摘要： 脑小血管病和衰弱为老年人群的常见疾病，二者常共病且关系密切。了解脑小血管病和衰弱的共同病因和发病机制，关注二者相关性研究现状和存在问题，尽可能实现早期诊断与干预，有助于改善老年人群的健康状况和生活质量。

关键词: 大脑小血管疾病, 蛋白质能量营养不良, 综述

Abstract: Cerebral small vascular disease (cSVD) and frailty are common in the elderly, and they tend to co-exist with similar risk factors. It is important to understand the etiology and pathogenesis of cSVD and frailty, and focus on the research frontier problems. Meanwhile, early diagnosis and intervention of these two diseases can help to improve health and quality of life.

Key words: Cerebral small vascular diseases, Protein-energy malnutrition, Review