摘要：

多发性硬化是临床常见的中枢神经系统脱髓鞘疾病，可伴发认知功能障碍，其发生机制迄今尚未阐明。越来越多MRI 新技术的广泛应用，为从神经影像学角度阐述多发性硬化伴认知功能障碍的发生机制提供重要依据。本文对近年关于多发性硬化伴认知功能障碍的MRI研究进展进行概述。

关键词: 多发性硬化, 认知障碍, 磁共振成像, 综述

Abstract:

Multiple sclerosis (MS) is a common inflammatory demyelinating disease that affects the central nervous system (CNS). It may be accompanied by cognitive impairment, however, the mechanism for cognitive impairment in multiple sclerosis is still unknown. More and more MRI techniques are used to improve the understanding on pathogenetic mechanism of cognitive impairment in multiple sclerosis. This paper summarizes MRI measures currently available to explain the possible mechanism for cognitive impairment of multiple sclerosis.

Key words: Multiple sclerosis, Cognition disorders, Magnetic resonance imaging, Review