中国现代神经疾病杂志 ›› 2015, Vol. 15 ›› Issue (1): 5-9. doi: 10.3969/j.issn.1672-6731.2015.01.003

• 神经科学发展史 • 上一篇    下一篇

2 高血压与脑卒中发展史

李青, 武剑   

  1. 100053 北京,首都医科大学宣武医院神经内科 北京市脑重大疾病研究院脑卒中研究所
  • 出版日期:2015-01-25 发布日期:2015-01-20
  • 通讯作者: 武剑 (Email:wjxr@yahoo.com)
  • 基金资助:

    国家自然科学基金资助项目(项目编号:81371291);北京市科技计划重点项目(项目编号:D111107003111006);北京市卫生系统高层次卫生技术人才培养计划项目( 项目编号:2013-2-034);北京市卫生系统“ 十百千”卫生人才“ 十”层次人才项目

Development history of hypertension and stroke

LI Qing, WU Jian   

  1. Department of Neurology, Xuanwu Hospital, Capital Medical University; Beijing Institute for Brain Disorders Stroke Research Institution, Beijing 100053, China
  • Online:2015-01-25 Published:2015-01-20
  • Contact: WU Jian (Email: wjxr@yahoo.com)
  • Supported by:

    This study was supported by National Natural Science Foundation of China (No. 81371291), Major Project of Beijing Municipal Science & Technology Commission (No. D111107003111006), High-level Technical Training Project Funding of Beijing Health System (No. 2013-2-034) and The Ten Level of
    Beijing "Ten, Hundred and Thousand" Talent Project.

摘要: 目前,我国高血压患病率呈逐年升高之趋势,而国人对高血压的知晓率、诊断率、控制率明显低于发达国家水平。20 世纪,研究者通过对不同国家、不同人种的综合分析,发现高血压可使脑卒中风险增加,抗高血压药物的应用可明显降低脑卒中发生率和复发率;21 世纪,研究者将目光转向诊室外血压监测,24 小时动态血压监测研究发现不同时间段血压水平与脑卒中发病的关系有所不同,以夜间血压的影响较大,而家庭血压监测则可更全面、真实地提供长期血压变化;未来,将通过对血压的全面监测与治疗,以遏制目前脑卒中“井喷”之景。

关键词: 卒中, 高血压, 医学史, 综述

Abstract: Stroke affects people's quality of life because of its high morbidity and mortality. In China, stroke is easily affected by hypertension, and the morbidity of hypertension is rising quickly year by year. However, most of adults who have hypertension do not know about their disease. In the 20th century, researchers focused on the relationship between blood pressure and stroke, and found that hypertension could lead to stroke. The incidence and recurrence of stroke could be decreased through antihypertensive treatment. In the 21th century, researchers gradually transfer their attention to the daily monitoring of blood pressure. The ambulatory blood pressure monitoring reveals that blood pressures during different periods of one day have different correlations with stroke occurrence. Home blood pressure monitoring (HBPM) provides longtime blood pressure changes. In the future, after the overall monitoring and treatment of hypertension, we believe that we can decrease the overflow of stroke prevalence.

Key words: Stroke, Hypertension, History of medicine, Review