Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (5): 817-821.doi: 10.16352/j.issn.1001-6325.2023.05.0817

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Progress on the role of histidine phosphatase in the occurrence of some diseases

GUO Ge, LIU Chunlei*   

  1. Translation Medicine Research Center, Medical Innovcation Research Division of Chinese People's Liberation Army General Hospital, Beijing 100853, China
  • Received:2021-12-17 Revised:2022-06-29 Online:2023-05-05 Published:2023-04-26
  • Contact: *

Abstract: Protein phosphorylation is involved in the regulation of a variety of biological processes. Histidine phosphatase dephosphorylates proteins containing histidine phosphorylation. Therefore, histidine phosphatase dysfunction can lead to the occurrence of a variety of clinical diseases, such as tumors, metabolic diseases, etc. This review summarizes the composition of histidine phosphatase, the relationship between histidine phosphatase and clinical diseases in orer to provide a new pathway for the clinical treatment of diseases.

Key words: histidine phosphatase, diseases

CLC Number: