Basic & Clinical Medicine ›› 2017, Vol. 37 ›› Issue (11): 1640-1643.

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Research progress in molecular connection between autophagy and inflammation


  1. 1. 总医院
  • Received:2016-10-08 Revised:2016-12-22 Online:2017-11-05 Published:2017-11-01

Abstract: Autophagy is a so important metabolism mechanism that involved in various stress responses of cells such as inflammation. A close molecular connection between autophagy and inflammation. One side, some inflammatory mediators can regulate autophagy and its translation; The other side, autophagy is able to suppress the excessive inflammation in various manners. Therefore, deficient autophagy may associate with inflammatory diseases such as Crohn’s Disease (CD).

Key words: Autophagy, inflammation, Crohn’s Disease