Advance of long non-coding RNAH19 in cancer

Basic & Clinical Medicine ›› 2016, Vol. 36 ›› Issue (8): 1150-1153.

Advance of long non-coding RNAH19 in cancer

Received:2015-11-19 Revised:2015-12-25 Online:2016-08-05 Published:2016-07-13

Abstract

Abstract: Long non-coding RNA(LncRNA) H19 associates with cancer. It plays a cancer promoting role in lung cancer, breast cancer and stomach cancer, but H19 has dual effect in hepatocellular carcinoma. The mechanism of H19 is still unclear. It may regulated by miR-675, expression of oncogenes, formatting of EMT and the imprinting status of IGF2 under methylation. H19 might be a valuable potential biomarker of cancer.

Key words: Long non-coding RNA, H19, cancer, biomarker

CLC Number:

R730

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Advance of long non-coding RNAH19 in cancer

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