Abstract: iPS provides a new way for the study of disease pathogenesis,drug discovery and regenerative medicine.Despite the rapid progress has been made in the iPS cell technology,the reprogramming of iPS is still unclear.Mitochondria is an important participant in various physiological processes in the cell.The effect of mitochondria on the iPS reprogramming and the relationship between them need to be studied.

Key words: iPS, mitochondria, reprogramming