Abstract: Foreign gene targeting transfection into vivo and highly expression are the fundation of investigating gene function and gene therapy. The hydrodynamics-based transfection founded in recent years can deliver plasmid into animal cells conveniently, quickly, safely, efficiently, and gene can highly, stably express. This paper introduces the concept, mechanism and application of hydronamic gene delivery.

Key words: hydronamics-based tail-vein transgene technology, orgain targeting, gene function, gene therapy