Basic & Clinical Medicine ›› 2009, Vol. 29 ›› Issue (9): 999-1001.
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Ting-ting LI, Yuan GUO
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Abstract: Heme oxygenase-1 (HO-1) is an inducible stress protein. In addition to its role in heme degradation, several positive biological effects exerted by this enzyme have gained attention, as anti-in?ammatory, anti-apoptotic, anti-proliferative and cytoprotective functions. This oxidase system with wide function takes part in the pathophysiology of cardiovascular system. It is related to multiple cardiovascular diseases including hypertension, atherosclerosis, ischemia /reperfusion injury and postangioplasty restenosis.
Key words: heme oxygenase-1, carbon monoxide, bilirubin, hypertension, atherosclerosis
Ting-ting LI; Yuan GUO. Progress in research on the role of heme oxygenase - 1 in cardiovascular diseases[J]. Basic & Clinical Medicine, 2009, 29(9): 999-1001.
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