Progress in the treatment of acute lung injury with Mesenchymal stem cells

Basic & Clinical Medicine ›› 2009, Vol. 29 ›› Issue (9): 1002-1006.

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Progress in the treatment of acute lung injury with Mesenchymal stem cells

Li-kun ZHENG, Lei ZHANG, Nai-yao CHEN, Shou-ling WU, Hui ZHAO

North China Coal Medical College Kailuan Hospital Affiliated to North China Coal Medical College

Received:2008-10-27 Revised:2008-12-04 Online:2009-09-20 Published:2009-09-20

Abstract

Abstract: Mesenchymal stem cell is a kind of multipotent hematopoietic stem cell. In the acute lung injury, it can differentiate into TypeⅠand TypeⅡepithelial cell, and repair impaired organization. In addition, mesenchymal stem cells have benefit effects in the treatment of lung injury by reducing proinflammatory factors IL-1,MIP-2,INF-γ, TNF-α, increasing antiinflammatory factors IL-10,IL-1ra, IL-13 and alleviating inflammatory response to the acute lung injury.

Key words: acute lung injury, mesenchymal stem cells, inflammatory response

CLC Number:

R563.9

Li-kun ZHENG; Lei ZHANG; Nai-yao CHEN; Shou-ling WU; Hui ZHAO. Progress in the treatment of acute lung injury with Mesenchymal stem cells[J]. Basic & Clinical Medicine, 2009, 29(9): 1002-1006.

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Progress in the treatment of acute lung injury with Mesenchymal stem cells

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