Basic & Clinical Medicine ›› 2008, Vol. 28 ›› Issue (5): 512-515.
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Jin-bao ZONG, Xue-mei XU
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Abstract: A variety of heat shock protein 70(HSP70)-associated therapeutic vaccines have been developed in anti-tumor immunotherapy, including protein vaccine, peptide vaccine, tumor cell vaccine and DNA vaccine, etc, in which HSP70-fused DNA vaccine attracts our attention with its superiority, it not only induces consistent anti-tumor immune response but also helps sustain immune memory. In this article we reviewed the function and application of HSP70 in the therapeutic tumor DNA vaccine.
Jin-bao ZONG; Xue-mei XU. Research progress on the DNA vaccine of HSP70 fused with tumor antigen gene[J]. Basic & Clinical Medicine, 2008, 28(5): 512-515.
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2008/V28/I5/512