Abstract: Objective To explore the application effect of micro-lecture combined with case-based learning (CBL) in the teaching of pharmacotherapeutics for undergraduate nursing students. Methods Two classes of undergraduate nursing students from School of Nursing, Peking Union Medical College enrolled in 2021 were selected as the research subjects. They were taught by micro-lecture combined with CBL (experimental group) or traditional lecture-based learning (LBL) (control group) respectively; The students' in-class quiz and final exam scores were collected. The questionnaires were distributed to evaluate the teaching effect and learning experience through analyzing the scores and questionnaire results. Results The in-class quiz scores of the experimental group were 77.52±17.68, and those of the control group were 66.34±21.35; The final exam scores of the experimental group were 64.34±26.17, and those of the control group were 52.33±25.55. The scores of the experimental group in both tests were significantly higher than those of the control group, and the differences were statistically significant (P＜0.01). The questionnaire findings indicated that the experimental group improved on the theoretical understanding, knowledge retention, medication practice proficiency, interest in learning, concentration in class, and interaction willingness in comparison to the control group. Conclusions Micro-lecture combined with CBL can enhance the learning effect of pharmacotherapeutics for undergraduate nursing students, and optimize the learning experience. It is worth to be further improved and promoted as a feasible teaching method.

Key words: undergraduate nursing student, pharmacotherapeutics, micro-lecture, case-based learning