Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (5): 790-793.doi: 10.16352/j.issn.1001-6325.2023.05.0790

• Clinical Sciences • Previous Articles     Next Articles

Effect of compound α-ketoacid on quality of life and self-perceived burden in diabetic patients undergoing peritoneal dialysis

YIN Yue, WANG Liyan, HUANG Hongdong*   

  1. Department of Nephrology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
  • Received:2023-01-05 Revised:2023-03-23 Online:2023-05-05 Published:2023-04-26
  • Contact: *

Abstract: Objective To compare effects of compound α-ketoacids on quality of life(QOL) and self-perceived burden(SPB) of diabetes patients undergoing peritoneal dialysis. Methods Totally 86 diabetes patients received continuous ambulatory peritoneal dialysis(CAPD) for more than 3 months in Friendship Hospital were divided into observation group (n=44) and treatment group (n=42). After 6 months of treatment, the quality of life of both groups was assessed with the World Health Organization Quality of Life Scale-brief Form Questionnaire(WHOQOL-BREF) and the self-perceived burden was assessed with the Self-perceived Burden Scale (SPBS). Results After 6 months, the glycosylated hemoglobin in the treatment group was 5.72%±1.03%, which was significantly lower than 6.70%±1.17% found in observation group. The physiological field, environmental field and total score of treatment group was significantly higher than those in observation group(P<0.05), and there was no difference was found self-perceived burden. Conclusions Simultaneous administration of peritoneal dialysis plus compound α-ketoacids supplement may significantly improve the quality of life of diabetes patients.

Key words: compound α-ketoacid, peritoneal dialysis, diabetic patients, self-perceived burden, glycosylated hemoglobin

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