Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (11): 1771-1775.doi: 10.16352/j.issn.1001-6325.2022.11.1771

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Research progress of umbilical cord mesenchymal stem cells in repairing skin wounds

WU Wen-zhe1, SUN Jian-wei3, FU Chang-xiu1, HUANG Li-chen-lu1, ZHENG Yong-qin2, HE Jun-dong2*   

  1. 1. Medical Faculty, Kunming University of Science and Technology, Kunming 650000;
    2. Department of Endocrinology and Metabolism; 3. Department of Breast and Thyroid Surgery, the First People's Hospital of Yunnan Province,the Affiliated Hospital of Kunming University of Science and Technology, Kunming 650000,China
  • Received:2021-06-03 Revised:2021-11-25 Online:2022-11-05 Published:2022-11-01
  • Contact: *

Abstract: Umbilical cord mesenchymal stem cells (UC-MSCs) are a kind of adult stem cells with low immunogenicity, which are easy to collect and to expand in vitro. UC-MSCs can regulate wound inflammation, promote angiogenesis and cell proliferation, inhibit scar formation and induce the formation of skin appendages. UC-MSCs combined with other drugs can promote the adhesion, survival, migration and proliferation of UC-MSCs.

Key words: umbilical cord mesenchymal stem cells, inflammation response, proliferation, adhesion, migration

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