COVID-19患者腹泻发生机制研究进展

基础医学与临床 ›› 2021, Vol. 41 ›› Issue (11): 1684-1687.

COVID-19患者腹泻发生机制研究进展

张少罡, 王冬, 宋洁, 张晓岚^*

河北医科大学第二医院消化内科, 河北石家庄 050000

收稿日期:2021-03-15 修回日期:2021-08-13 发布日期:2021-10-27
通讯作者: *xiaolanzh@126.com

Research progress on the mechanism of diarrhea in patients with COVID-19

ZHANG Shao-gang, WANG Dong, SONG Jie, ZHANG Xiao-lan^*

Department of Gastroentology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China

Received:2021-03-15 Revised:2021-08-13 Published:2021-10-27
Contact: *xiaolanzh@126.com

摘要/Abstract

摘要： 新型冠状病毒肺炎(COVID-19)患者主要表现为发热、咳嗽等呼吸系统症状,但需警惕部分患者伴随消化系统症状,如腹泻、恶心、呕吐等,甚至少数患者以腹泻等不典型症状为首发表现。新型冠状病毒2(SARS-CoV-2)感染肠上皮细胞、肠道菌群失调、治疗药物、精神心理因素、细胞因子风暴及原发基础疾病加重等可导致COVID-19患者出现腹泻,临床医师应提高对COVID-19患者表现为消化系统症状的警惕性,并对有腹泻表现的COVID-19患者进行及时有效的治疗。

关键词: COVID-19, 腹泻, 机制

Abstract: Patients with corona virus disease 2019(COVID-19) mainly have fever, cough and other respiratory symptoms, but it is necessary to be aware that some patients are complicated by digestive symptoms, such as diarrhea, nausea and vomiting, and even a few patients show atypical symptoms such as diarrhea as the first presentation. This article reviews the mechanism of SARS-CoV-2 infection with digestive tract symptoms,change of intestinal microbiota, therapeutic drugs, psychosocial factors, cytokine storm and aggravation of primary underlying diseases, etc., so as to sharpen clinicians vigilance against COVID-19 patients with digestive system symptoms, and provide theoretical basis for corresponding treatment.

Key words: COVID-19, diarrhea, mechanism

中图分类号:

R512.99

张少罡, 王冬, 宋洁, 张晓岚. COVID-19患者腹泻发生机制研究进展[J]. 基础医学与临床, 2021, 41(11): 1684-1687.

ZHANG Shao-gang, WANG Dong, SONG Jie, ZHANG Xiao-lan. Research progress on the mechanism of diarrhea in patients with COVID-19[J]. Basic & Clinical Medicine, 2021, 41(11): 1684-1687.

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