基础医学与临床 ›› 2014, Vol. 34 ›› Issue (6): 840-843.

• 临床园地 • 上一篇    下一篇

PET/CT 在诊断克罗恩病中的应用

严雪敏1,朱朝晖2,孙钢3,钱家鸣4   

  1. 1. 北京协和医院消化科
    2. 中国医学科学院 北京协和医学院, 北京协和医院心脏外科
    3. 中国医学科学院北京协和医学院北京协和医院消化内科
    4. 北京协和医院消化内科
  • 收稿日期:2013-04-17 修回日期:2013-10-09 出版日期:2014-06-05 发布日期:2014-05-26
  • 通讯作者: 严雪敏 E-mail:xhyxm2011@sina.com

PET/CT is applied in diagnosis of Crohn’s disease

  • Received:2013-04-17 Revised:2013-10-09 Online:2014-06-05 Published:2014-05-26
  • Contact: Xue-Min YAN E-mail:xhyxm2011@sina.com

摘要: 目的克罗恩病的诊断及鉴别诊断十分困难。探讨18F-PET/CT检查对其诊断的价值。方法:收集并分析2012年6月至2012年8月间北京协和医院消化科3例临床诊断较困难的炎症性肠病患者的临床资料,及PET/CT检查对其诊断的价值。结果患者1行18F-PET/CT检查提示结肠节段性病变,其肠道SUV值与肝脏类似;患者2行18F-PET/CT检查提示肠道多发节段性病变,病变肠道SUV值2倍于肝脏。均诊断为炎症性肠病,克罗恩病可能性大,予相应治疗后效果较好;患者3行18F-PET/CT检查提示病变肠道SUV值4倍于肝脏,不除外肿瘤。经手术证实为肠道T细胞淋巴瘤。结论:对疑似克罗恩病的患者,18F-PET/CT是一种很好的无创检查手段。目前,昂贵的检查费用限制了18F-PET/CT检查的广泛应用。

关键词: 关键词:克罗恩病, PET/CT, 诊断, 评估, 无创

Abstract: Objective Crohn’s disease (CD) is a chronic inflammatory disease involving the gastrointestinal tract with a tendency toward remission and relapse, and sometimes hardly be diagnosed until taken operation. It is said that 18F-PET/CT is a novel non-invasive technique for differential diagnosis and assessment of Crohn’s disease. Methods 3 patients were included from June 2012 to Augest 2012 in PUMCH, all have done the 18F-PET/CT. Results Patient 1, there were many abnormal areas with high FDG uptake in intestinal tract which standardized uptake value (SUVmax) were similar to in liver. Patient 2, the SUVmax was twice higher than in liver. Patient 3, it was more than 4-fold. Patient 1 and 2 were considered as CD, and patient 3 was T-cell lymphoma. Conclusions 18F-PET/CT is a novel non-invasive technique, but high-tech and expensive, for patient who is suspected for CD .

Key words: Key words:Crohn’s disease, PET/CT, diagnosis, assessment , non-invasive

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