基础医学与临床 ›› 2011, Vol. 31 ›› Issue (6): 679-682.

• 研究论文 • 上一篇    下一篇

针刺镇痛在分娩中的作用及其机制

朱庆双,王凤英,孙晓燕   

  1. 首都医科大学宣武医院
  • 收稿日期:2011-01-05 修回日期:2011-03-23 出版日期:2011-06-05 发布日期:2011-06-06
  • 通讯作者: 王凤英 E-mail:wfy509@yahoo.com

Acupuncture analgesia in childbirth the function and mechanism

Qing-shuang ZHU1,Feng-ying WANG1,Xiao-yan SUN2   

  1. 1. Xuanwu Hospital, Capital Medical University
    2.
  • Received:2011-01-05 Revised:2011-03-23 Online:2011-06-05 Published:2011-06-06
  • Contact: Feng-ying WANG E-mail:wfy509@yahoo.com

摘要: 目的 观察针刺对分娩镇痛的临床效果及作用机制,寻找一种安全有效、简便可行的分娩镇痛方法。 方法 随机抽样法选择针刺组16例、针刺+电刺激组29例和对照组46例,以视觉模拟评分疼痛分级法(VRS)评定镇痛效果,记录产程进展及产后出血情况、新生儿Apgar评分及体质量,观察针刺对母婴的影响。用高效液相色谱法(HPLC)检测针刺前后外周血中去甲肾上腺素(NA)及β-内啡肽(β-EP)含量变化,探讨该方法的镇痛机制。结果 针刺镇痛后VAS评分下降,疼痛缓解率82.76%,明显高于对照组的17.94%,并明显提高外周血中β-EP浓度,针刺后血β-EP及NA分别为5.20±0.93 mg/L及1230±18ng/L,显著高于对照组的4.38±0.67mg/L及783±31ng/L(P<0.05)。 结论 针刺能有效减轻第一产程分娩疼痛, 其镇痛效果可能是通过针刺使脑内具有镇痛作用的递质β-EP含量明显增加有关。

关键词: 针刺镇痛, 分娩, 产程

Abstract: Objective Observation of labor analgesia acupuncture and action mechanism of the clinical effect, looking for a safe and effective, simple and convenient method of labor analgesia. Methods The stochastic sampling method choice acupuncture group 16 examples, the acupuncture + electricity stimulation group 29 examples and the control group 46 examples, (VRS ache staging) evaluate the analgesic effect by the visual simulation grading law, the record course of childbirth progress and the postpartum hemorrhage situation, the newborn Apgar grading and the newborn body mass, the observation acupuncture to the maternal infant the influence. (HPLC) examines around the acupuncture with the highly effective liquid phase chromatography in the peripheral blood noradrenalin (NA) and β-endorphin (β-EP) the content change, discusses this method the analgesia mechanism. Results After acupuncture analgesia, the VAS grading drops, the ache alleviation rate 82.76%, are higher than the control group obviously 17.94%, and enhances in obviously the peripheral blood β-EP the density, after the acupuncture, the blood β-EP and NA respectively be 5.20±0.93 mg/L and 1230±18ng/L, obviously is higher than the control group 4.38±0.67mg/L and 783±31ng/L(P<0.05). Conclusions The acupuncture can reduce the first course of childbirth childbirth ache effectively, its analgesic effect possibly is enables in the brain through the acupuncture to have the analgesia function to hand over the nature β-EP content to increase obviously concerns.

Key words: Acupuncture analgesia, Childbirth, labor