Abstract: Objective To retrospectively review 19 cases of renal epithelioid angiomyolipoma (REAML) and to explore the clinical characteristics and diagnostic Methods in order to optimize diagnosis and clinical treatment. Methods Clinical data of 19 patients with REAML admitted to the hospital from June 2020 to March 2024 were reviewed for clinical characteristics of the disease, surgical procedure and follow-up outcomes. Results All 19 patients received successful laparoscopic surgery. Among them, 16 cases received retroperitoneal laparoscopic partial nephrectomy and 3 cases received retroperitoneal laparoscopic radical nephrectomy.Post-operative pathological diagnoses indicated that all cases were classified as renal epithelioid angiomyolipoma. After 4-45 months of follow-up, no tumor recurrence or metastasis was observed. Conclusions Renal epithelioid angiomyolipoma is a rare clinical disease with potential malignant transformation as recurrence and metastasis. Complete resection of the tumor by surgery is an effective treatment. Retroperitoneal laparoscopic partial nephrectomy is the first choice.

Key words: renal epithelioid angiomyolipoma, renal tumor, clinical characteristics