Abstract: Objective To investigate the surgical treatment principles of temporal lobe epilepsy caused by cavernous malformation and the surgical resection extent of the cavernous malformation. Methods The clinical data and follow-up results of 14 patients presented with temporal lobe epilepsy due to cavernous malformation admitted to the Department of Neurosurgery of Peking Union Medical College Hospital from May 2013 to Oct 2017 were retrospectively analyzed. The outcome of epilepsy control was assessed by the classification method proposed by International League Against Epilepsy in 2001. Results There were no deaths. No long-term neurological dysfunction was found in all patients. The last follow-up showed that 13 patients (92.8%) had no seizures throughout the year. Conclusion The patients with temporal lobe epilepsy due to cavernous malformation may receive maximized seizure control from surgical treatment, performed after the comprehensive evaluation of the patient's history, preoperative magnetic imaging and electrophysiological monitoring during the operation.

Key words: Epilepsy, Cavernous malformation, Temporal lobe, Surgery, Prognosis