Abstract: Objective To investigate the early diagnosis of neurogenic pulmonary edema in coma patients with cerebral hemorrhage, and to formulate the treatment plan and evaluate the curative effect according to the pathogenesis of neurogenic pulmonary edema. Methods This was a retrospective study of 120 coma patients with cerebral hemorrhage, admitted to the Neurosurgery Department of the Yan'an University Affiliated Hospital between April 2011 and September 2016. Sixty patients in the treatment group received the therapies of dilating blood vessel, reducing blood vessel permeability and enhancing colloid osmotic pressure. Sixty patients in the control group did not receive the therapies above. The respiratory rate, the number of sputum suction, the saturation of blood oxygen, the chest CT, and the complications caused by pulmonary complications within 3 weeks were observed.Results The respiratory rate, the number of sputum suction and the changes of blood oxygen saturation were significantly different 3 days after treatment in two groups(P<0.05). Chest CT within 3 days after treatment revealed that double symmetrical, cloudy or patchy changes of bilateral pulmonary pleural effusion aggravated in 91 patients, which were different compared with the beginning (P<0.05). Within 3 weeks, the treatment group had 5 cases of adverse pulmonary complications, which were significantly less than 29 cases in the control group (P < 0.05).Conclusion In coma patients with cerebral hemorrhage, it is an effective measure to treat neurogenic pulmonary edema by expanding blood vessel, reducing blood vessel permeability and enhancing colloid osmotic pressure.

Key words: Cerebral Hemorrhage, Coma, Early, Neurogenic Pulmonary Edema, Treatment