Abstract: Heart failure as a common cause of a variety of cardiovascular disease and the main cause of death, early diagnosis and effective intervention is to improve the prognosis of patients and an important means of outcome. Galectin-3 is a new biomarker of myocardial fibrosis and heart failure in recent years. It plays a certain role in the diagnosis and treatment of heart failure.Galectin-3 plays a key role in ventricular remodeling and heart failure, which can be used as a new target for treatment of heart failure.

Key words: galectin-3, heart failure, ventricular remodeling, inflammatory, fibrosis.