Abstract: From the natural-philosophical model of medicine in ancient Greece to the modern bio-psycho-social paradigm, the evolution of medical models has always been shaped by philosophy. In classical antiquity, medicine and philosophy were closely intertwined; the natural-philosophical model, exemplified by Hippocrates, emphasized the human body as an integrated whole. During the Renaissance, the rise of experimental science challenged traditional philosophical systems and pushed medicine toward empirical investigation. In the late twentieth century, the bio-psycho-social model emerged to address the limitations of the purely biomedical approach. In the twenty-first century, the advent of artificial intelligence is driving a new transformation in medicine and continually prompting reflection on the future direction of medical models and their underlying philosophical significance.

Key words: medical model, medical education, philosophy, artificial intelligence