Abstract: The CRISPR/Cas9 gene editing technology has been widely used in the biomedical field due to its unique advantages. The use of this technology has made great progress in related research on cardiovascular diseases such as cardiomyocyte levels, establishment of animal models of congenital heart disease, risk factors for coronary heart disease, arrhythmia, heart failure and cardiomyopathy, but the current gene editing technology still faces many problems in practical application.

Key words: CRISPR/Cas9 gene editor, cardiovascular diseases, basic research, clinical transformation, gene therapy