Progress of key genes involved in renal cell carcinoma

Basic & Clinical Medicine ›› 2011, Vol. 31 ›› Issue (8): 955-958.

Progress of key genes involved in renal cell carcinoma

Qing-hai WANG¹,Bing-bing SHI²

1. Dept．of Urology，PUMC Hospital，CAMS & PUMC
2. PUMC Hospital，CAMS & PUMC

Received:2011-03-22 Revised:2011-04-28 Online:2011-08-05 Published:2011-07-13
Contact: Qing-hai WANG E-mail:495158203@qq.com

Abstract

Abstract: Renal cell carcinoma is a type of multi-gene-related cancer, different subtype with a different histology, having a different clinical characteristics, responding differently to therapy and caused by different genes. Therefore, studying the related genes of cancer of the kidney has significant implications not only in depth understanding of the pathogenesis of renal cell carcinoma, but also in clinical application. This article reviews the major involved kidney cancer genes,such as VHL, PBRM1, MET, FH, BHD, etc., and analyzes their value in diagnosis and treatment of renal cell carcinoma.

Key words: renal cell carcinoma, genes

CLC Number:

R737.11

Qing-hai WANG Bing-bing SHI. Progress of key genes involved in renal cell carcinoma[J]. Basic & Clinical Medicine, 2011, 31(8): 955-958.

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Progress of key genes involved in renal cell carcinoma

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