Molecular mechanisms of selenium binding protein 1 expression regulation in cancer cells

doi:10.16352/j.issn.1001-6325.2025.09.1224

Abstract

Abstract: Selenium binding protein 1 (SELENBP1) is a protein related to selenium metabolism. Studies have found that SELENBP1 is abnormally expressed in various cancer cells, and its expression level is closely related to tumor occurrence, development, metastasis, and prognosis. Therefore, SELENBP1 is widely concerned, and its role in bladder cancer is being studied in-depth. This article mainly summarizes the expression regulation, biological functions, and potential molecular pathways of SELENBP1 in thyroid cancer, colorectal cancer, non-small cell lung cancer, prostate cancer, oral squamous cell cancer, and bladder cancer. The research results may provide a reference for understanding the mechanisms of SELENBP1 in cancer cells and offer new ideas and targets for tumor diagnosis and prevention.

Key words: selenium binding protein 1, cancer cell, molecular regulation, targeted therapy

CLC Number:

KANG Lei, ZHU Junlan. Molecular mechanisms of selenium binding protein 1 expression regulation in cancer cells[J]. Basic & Clinical Medicine, 2025, 45(9): 1224-1228.

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