慢性压力对乳腺癌发展的影响

doi:10.16352/j.issn.1001-6325.2024.09.1303

基础医学与临床 ›› 2024, Vol. 44 ›› Issue (9): 1303-1307.doi: 10.16352/j.issn.1001-6325.2024.09.1303

慢性压力对乳腺癌发展的影响

苏凌峰¹, 王虎霞², 王延峰³, 宋张骏^3*

1.西安医学院研究生处,陕西西安 710021;
2.陕西省肿瘤医院乳腺科,陕西西安 710065;
3.陕西省人民医院肿瘤外科,陕西西安 710068

收稿日期:2023-12-20 修回日期:2024-03-29 出版日期:2024-09-05 发布日期:2024-08-30
通讯作者: ^*doctorsong051107@126.com
基金资助:
陕西省自然科学基础研究计划(2022JZ-57);陕西省人民医院2023年科技发展孵化基金(2023YJY-19)

Impact of chronic stress on the development of breast cancer

SU Lingfeng¹, WANG Huxia², WANG Yanfeng³, SONG Zhangjun^3*

1. Graduate School of Xi′an Medical University, Xi′an 710021;
2. Department of Galactophore, Shaanxi Provincial Cancer Hospital, Xi′an 710065;
3. Department of Surgical Oncology, Shaanxi Provincial People′s Hospital, Xi′an 710068, China

Received:2023-12-20 Revised:2024-03-29 Online:2024-09-05 Published:2024-08-30
Contact: ^*doctorsong051107@126.com

摘要/Abstract

摘要： 乳腺癌是导致女性肿瘤致死的主要因素,是世界上女性常见的癌之一。负面情绪中最常见的是焦虑和抑郁,焦虑和抑郁在乳腺癌患者中又尤其常见。在抑郁症的复杂病因中,慢性压力是一个主要的危险因素。压力导致细胞、分子和神经回路功能的失调从而促进抑郁症的发生,慢性压力通过相关神经递质促进乳腺癌的发生发展,同样也影响了乳腺癌患者的预后。

关键词: 乳腺癌, 慢性压力, 发病机制

Abstract: Breast cancer is one of the most common cancers of females and is a leading cause of tumor-related death in women. Negative emotion frequently presents in patients like anxiety and depression and chronic stress which may lead to depression is a major risk factor of the cancer development. Stress leads to dysfunctions of cells, molecules and neural circuits, thus promoting depression. Chronic stress promotes the occurrence and development of breast cancer through related neurotransmitters and also affects the prognosis of breast cancer patients.

Key words: breast cancer, chronic stress, pathogenesis

中图分类号:

R737

苏凌峰, 王虎霞, 王延峰, 宋张骏. 慢性压力对乳腺癌发展的影响[J]. 基础医学与临床, 2024, 44(9): 1303-1307.

SU Lingfeng, WANG Huxia, WANG Yanfeng, SONG Zhangjun. Impact of chronic stress on the development of breast cancer[J]. Basic & Clinical Medicine, 2024, 44(9): 1303-1307.

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慢性压力对乳腺癌发展的影响

Impact of chronic stress on the development of breast cancer

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