长期低剂量抗生素的暴露对孕妇及婴幼儿的影响

基础医学与临床 ›› 2020, Vol. 40 ›› Issue (2): 253-256.

长期低剂量抗生素的暴露对孕妇及婴幼儿的影响

李曼玉, 尹婕, 马良坤^*

中国医学科学院北京协和医学院北京协和医院妇产科, 北京 100730

收稿日期:2019-07-08 修回日期:2019-12-02 出版日期:2020-02-05 发布日期:2020-02-05
通讯作者: ^*MaLiangKun@pumch.cn

Effects of long-term low-dose antibiotics exposure on the pregnant women and infants

LI Man-yu, YIN Jie, MA Liang-kun^*

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730,China

Received:2019-07-08 Revised:2019-12-02 Online:2020-02-05 Published:2020-02-05
Contact: ^*MaLiangKun@pumch.cn

摘要/Abstract

摘要： 抗生素的不当使用可导致严重的妊娠并发症及产褥期疾病的发生。同时抗生素的暴露能够影响生命体早期肠道微生态构建,进而导致后代免疫系统疾病、神经系统疾病及代谢性疾病发病率的增加。然而,长期低剂量抗生素的研究尚处于动物实验阶段。

关键词: 抗生素, 孕产妇, 婴幼儿, 肠道菌群

Abstract: Improper use of antibiotics can lead to serious pregnancy complications and puerperal disorders. At the same time, the exposure to antibiotics can affect the construction of intestinal microecology in the early stage of life, and then lead to the increase of the morbidity rate of immune system diseases, nervous system diseases and metabolic diseases. However, the research on long-term and low-dose antibiotics' exposure is still in the stage of animal experiments.

Key words: antibiotics, pregnancy, infants, intestinal microecology

中图分类号:

R715.3

李曼玉, 尹婕, 马良坤. 长期低剂量抗生素的暴露对孕妇及婴幼儿的影响[J]. 基础医学与临床, 2020, 40(2): 253-256.

LI Man-yu, YIN Jie, MA Liang-kun. Effects of long-term low-dose antibiotics exposure on the pregnant women and infants[J]. Basic & Clinical Medicine, 2020, 40(2): 253-256.

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