基础医学与临床 ›› 2011, Vol. 31 ›› Issue (10): 1185-1188.

• 短篇综述 • 上一篇    

血管生成抑制因子vasohibin的研究进展

白怀1,王芳2   

  1. 1. 四川大学华西第二医院
    2.
  • 收稿日期:2010-06-25 修回日期:2010-10-13 出版日期:2011-10-05 发布日期:2011-10-08
  • 通讯作者: 白怀 E-mail:baihuai60@yahoo.com.cn
  • 基金资助:
    院校级基金

Recent advances on angiogenesis inhibitor of vasohibin

  • Received:2010-06-25 Revised:2010-10-13 Online:2011-10-05 Published:2011-10-08

摘要: 人体正常血管生成取决于血管生成刺激因子和抑制因子的平衡调节。Vasohibin是迄今为止发现的唯一一个可以被血管内皮细胞生长因子(vascular endothelial cell growth factor, VEGF)或成纤维细胞生长因子-2(basic fibroblast growth factor, FGF-2)诱导的负反馈血管生成抑制因子。Vasohibin在调节生理和病理状态的血管生成中可能发挥重要作用。目前,vasohibin已成为相关医学领域受到重视的研究课题。

关键词: 血管生成 , vasohibin , 负反馈调节

Abstract: Angiogenic balance in physiological conditions is determined by the levels of angiogenesis activators and inhibitors. Vasohibin is a negative feedback regulator of angiogenesis inhibitor that can be induced by VEGF or bFGF. Vasohibin may play an important role in the regulation of angiogenesis under physiological and pathological conditions. Currently, vasohibin is an important research topic in a relevant field of medicine.

Key words: Angiogenesis, Vasohibin, Negative regulation

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