基础医学与临床 ›› 2021, Vol. 41 ›› Issue (1): 112-115.

• 短篇综述 • 上一篇    下一篇

急性缺血性卒中患者血栓成分和影像学表现的研究进展

刘佳奕1, 章正祥2*, 严民力2, 戚观树2, 陈强2, 侯群2   

  1. 1.浙江中医药大学 第一临床医学院, 浙江 杭州 310053;
    2.浙江中医药大学附属第一医院(浙江省中医院)神经内科, 浙江 杭州 310006
  • 收稿日期:2020-06-03 修回日期:2020-10-13 出版日期:2021-01-05 发布日期:2020-12-30
  • 通讯作者: *jxzhangzx@163.com
  • 基金资助:
    全国名老中医药专家传承工作室建设项目([2012]149);全国名老中医药专家传承工作室建设项目(饶旺福全国名老中医药专家传承工作室)([2016]42]

Research progress of thrombus compositions and imaging manifestations in patients with acute ischemic stroke

LIU Jia-yi1, ZHANG Zheng-xiang2*, YAN Min-li2, QI Guan-shu2, CHEN Qiang2, HOU Qun2   

  1. 1. the First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053;
    2. Department of Neurology, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou 310006, China
  • Received:2020-06-03 Revised:2020-10-13 Online:2021-01-05 Published:2020-12-30
  • Contact: *jxzhangzx@163.com

摘要: 近年来随着血管内介入治疗的快速发展,对急性缺血性卒中(AIS)患者血栓的研究日益加深,血栓的组成主要包括红细胞、纤维蛋白/血小板、白细胞、血管性血友病因子(vWF)及其他少见的成分,在非增强电子计算机断层扫描(NCCT)和磁共振成像(MRI)上可分别表现为动脉高密度征(HAS)及磁敏感血管征(SVS)。通过进一步分析其成分、影像学表现有助于了解AIS的病因、选择治疗方法、临床预后等。

关键词: 血栓成分, 白细胞, 血管性血友病因子(vWF), 动脉高密度征(HAS), 磁敏感血管征(SVS)

Abstract: With the rapid development of intravascular interventional treatment, the study of thrombus in patients with acute ischemic stroke (AIS) has been intensified in recent vears. The composition of thrombus mainly includes red blood cells, fibrin/platelets, white blood cells, and von Willebrand factor (vWF) and other rare components, which can be manifested as arterial hyperdensity sign (HAS) and susceptibility vessel sign (SVS) on non-contrast CT(NCCT) and magnetic resonance imaging (MRI). Further analysis of thrombus components and imaging manifestations will help to understand the etiology, treatment selection and clinical prognosis of AIS.

Key words: thrombus compositions, white blood cells, von willebrand factor(vWF), hyperdense artery sign(HAS), susceptibility vessel sign(SVS)

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