COVID-19的消化道受累

摘要/Abstract

摘要： 由新型冠状病毒(SARS-CoV-2)感染引起的新型冠状病毒肺炎(COVID-19)目前已在全球范围流行。该病以肺部受累为主要表现,但肺部以外的其他脏器损害也很常见,其中包括消化道受累,表现为腹泻、厌食、恶心等症状,以及粪便SARS-CoV-2核酸阳性。病理检查在消化道上皮细胞中可发现病毒颗粒。这些都表明消化道也是SARS-CoV-2的重要靶器官。本文总结了COVID-19消化道受累的相关文献,并阐述发病机制、临床表现及对疫情防控的意义。

关键词: SARS-CoV-2, COVID-19, 消化道症状

Abstract: Coronavirus disease 2019(COVID-19) has been a worldwide pandemic. Although the disease is mainly manifested by pulmonary involvement, still many COVID-19 patients present with other organ damage, including gastrointestinal involvement such as diarrhea, anorexia, nausea, and virus nucleic acid being found in fecal samples. Pathological examination demonstrates virus particles presence in epithelial cells of the digestive tract. These findings indicate that the digestive tract is also an important target organ of SARS-CoV-2. This paper reviews the relevant literatures on COVID-19 gastrointestinal involvement and summarizes the pathophysiological mechanism, clinical features, and implications for infection control and prevention.

Key words: SARS-CoV-2, COVID-19, gastrointestinal symptoms

中图分类号:

R512.99

宋锴, 吴东, 杨爱明. COVID-19的消化道受累[J]. 基础医学与临床, 2020, 40(7): 881-886.

SONG Kai, WU Dong, YANG Ai-ming. Gastrointestinal tract involvement of COVID-19[J]. Basic & Clinical Medicine, 2020, 40(7): 881-886.

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