半乳糖凝集素-7生物学功能研究进展

基础医学与临床 ›› 2020, Vol. 40 ›› Issue (3): 399-402.

半乳糖凝集素-7生物学功能研究进展

王然然, 姜双全, 李守强, 于丹丹, 冷晓萍^*

哈尔滨医科大学附属第二医院超声医学科, 黑龙江哈尔滨 150081

收稿日期:2019-05-05 修回日期:2019-11-05 出版日期:2020-03-05 发布日期:2020-03-02
通讯作者: ^*xpleng@ems.hrbmu.edu.cn
基金资助:
国家自然科学基金(81701720);黑龙江省自然科学基金杰出青年项目(JQ2019H001)

Research advances on biological functions of galectin-7

WANG Ran-ran, JIANG Shuang-quan, LI Shou-qiang, YU Dan-dan, LENG Xiao-ping^*

Department of Ultrasonography,the Second Affiliated Hospital of Harbin Medical University, Harbin 150081,China

Received:2019-05-05 Revised:2019-11-05 Online:2020-03-05 Published:2020-03-02
Contact: ^*xpleng@ems.hrbmu.edu.cn

摘要/Abstract

摘要： 半乳糖凝集素 (galectins) 是 β-半乳糖苷结合性动物凝集素的家族成员之一,存在于从线虫到哺乳动物等各种活性有机体内,参与细胞黏附、增殖和免疫反应等多种生物学过程。作为该家族重要成员之一的galectin-7,与上皮组织的分化和成熟、损伤表皮的再生、肿瘤的发生发展以及机体免疫具有密切联系。

关键词: galectin-7, 上皮再生, 细胞凋亡, 免疫应答

Abstract: Galectins construct a family of animal lectins for β-galactosides, which are widely distributed from living nematodes to mammals and other living organisms,participating in various biological processes, such as cell-cell adhesion, growth regulation and immune response.Galectin-7, one of the most important member of the family is closely related to the differentiation and maturation of epithelial tissues, the proliferation of injured epidermis, the development of tumors and the immunity of body.

Key words: galectin-7, re-epithelialization, apoptosis, immunology

中图分类号:

王然然, 姜双全, 李守强, 于丹丹, 冷晓萍. 半乳糖凝集素-7生物学功能研究进展[J]. 基础医学与临床, 2020, 40(3): 399-402.

WANG Ran-ran, JIANG Shuang-quan, LI Shou-qiang, YU Dan-dan, LENG Xiao-ping. Research advances on biological functions of galectin-7[J]. Basic & Clinical Medicine, 2020, 40(3): 399-402.

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