基础医学与临床 ›› 2019, Vol. 39 ›› Issue (1): 81-84.

• 临床研究 • 上一篇    下一篇

鼻咽联合手术改善340例阻塞性睡眠呼吸暂停低通气综合征的疗效

高云海,郭亿超   

  1. 北京华信医院
  • 收稿日期:2017-10-19 修回日期:2018-03-30 出版日期:2019-01-05 发布日期:2018-12-28
  • 通讯作者: 高云海 E-mail:18810258950@163.com

Improved treatment by combined naso-pharyngeal surgery for obstructive sleep apnea hypopnea syndrome in 340 cases

  • Received:2017-10-19 Revised:2018-03-30 Online:2019-01-05 Published:2018-12-28
  • Contact: Gao YunHai E-mail:18810258950@163.com

摘要: 目的 观察评价阻塞性睡眠呼吸暂停低通气综合征(OSAHS)鼻咽联合手术治疗的效果。方法 将于2014年12月至2016年12月收治的OSAHS鼻咽患者随机分为对照组,实施改良悬雍垂腭咽成形术(H-UPPP),联合治疗组实施H-UPPP联合鼻腔扩容术,比较两组治疗有效率及手术一般资料,比较术前术后MSpO2、LSpO2、SpO2、AHI指数、PSQI评分、ESS评分及并发症。 结果 联合治疗组治疗有效率明显高于对照组,平均住院时间,短于对照组(P<0.05);联合治疗组术后MSpO2、LSpO2明显高于对照组,而TS90%较对照组低(P<0.05);联合治疗组术后AHI指数、PSQI评分、ESS评分、并发症发生率低于对照组(P<0.05)。结论 H-UPPP联合鼻腔扩容术能显著改善患者血气分析指标及睡眠、呼吸质量,缩短住院时间,减少术后并发症,值得在临床推广应用。

关键词: [关键词] 阻塞性睡眠呼吸暂停低通气综合征, OSAHS, H-UPPP, 鼻腔扩容术

Abstract: Objective To observe the curative effects of combined surgical treatment on obstructive sleep apnea hypopnea syndrome (OSAHS). Methods Nasopharyngeal OSAHS patients were randomly divided the patients from December 2014 to December 2016 were as control group received uvulopalatopharyngoplasty (H-UPPP) .Combined treatment group, including implementation of H-UPPP combined with expansion nasal surgery. We compared two groups of treatment efficiency and operation data, comparing the preoperative and postoperative MSpO2, LSpO2, SpO2, AHI index, PSQI score, the ESS score and complications. Results The effective rate of the combined treatment group was significantly higher than that of the control group. The average time of hospitalization was shorter than that of the control group (P < 0.05). The MSpO2 and LSpO2 in the combo group were significantly higher than those in the control group, while TS90% was lower than that of the control group (P< 0.05). The incidence of AHI index, PSQI score, ESS score and complications after operation in the combined treatment group were lower than that of the control group (P < 0.05). Conclusions H-UPPP combined with nasal dilatation can significantly improve blood gas analysis index and sleep and breathing quality, shorten hospitalization time and reduce postoperative complications, which is worthy of clinical application.

Key words: [Key Words] Obstructive sleep apnea hypopnea syndrome, OSAHS, H-UPPP, Nasaldilatation