关键词: 调节性B细胞, 肿瘤, 细胞因子

Abstract: Regulatory B cells are a newly designated subset of B cells that have shown to play a significant role in inhibiting tumor immunity and promoting the proliferation and metastasis of tumor cells. Bregs can suppress diverse cell subtypes through the secretion of cytokines, such as IL-10, IL-35 and TGF-β, thus attenuating anti-tumor immune responses.

Key words: regulatory B cells, tumor, cytokines