基础医学与临床 ›› 2015, Vol. 35 ›› Issue (6): 772-775.

• 研究论文 • 上一篇    下一篇

六价铬污染地区居民的消化系统健康损害调查分析

王猛1,柳晓琳2,魏岚萍3,程晓萍2,许群1   

  1. 1. 中国医学科学院基础医学研究所 北京协和医学院基础学院
    2. 辽宁医学院
    3. 锦州市中心医院
  • 收稿日期:2015-04-02 修回日期:2015-04-14 出版日期:2015-06-05 发布日期:2015-05-27
  • 通讯作者: 许群 E-mail:xuqun@ibms.cams.cn
  • 基金资助:
    环保公益性行业科研专项

Investigation of digestive system damage of residents in areas polluted by hexavalent chromium

  • Received:2015-04-02 Revised:2015-04-14 Online:2015-06-05 Published:2015-05-27

摘要: 目的 探讨环境六价铬污染地区一般人群消化系统存在的健康问题。方法 在锦州某具有50年六价铬污染历史的铁合金厂附近,选择六价铬污染程度较重、较轻以及无污染的3个研究区域。采用整群随机抽样的方法,对2 473名居民做健康状况问卷调查。结果 按照六价铬污染程度由重到轻,3个研究区域的总消化系统症状(恶心、呕吐、消化不良、腹泻、腹痛、胃痉挛和嘴角糜烂)现患率依次为36.08%、8.23%和0.73%;肝胆疾病现患率依次为2.78%、1.51%和1.16%;消化性溃疡现患率依次为1.14%、0.50%和0.29%。各消化系统症状、肝胆疾病和消化性溃疡均明显呈现六价铬污染越重,患病风险越大的现象。胃肠炎、胰腺炎患病情况与六价铬污染程度未呈现明显相关。结论 长期生活在六价铬污染地区的人群存在一定的消化系统损害。

关键词: 六价铬, 污染, 环境暴露, 消化系统, 健康调查

Abstract: Objective To investigate the residents’ health status of digestive system in hexavalent chromium contaminated areas. Methods 2473 residents in Jinzhou were randomly selected from three villages near an alloy plant with 50 years of hexavalent chromium pollution by cluster sampling. The three villages are seriously polluted, slightly polluted and unpolluted areas, respectively. A questionnaire-based survey was conducted. Results According to the pollutant level from heavy to light, the total prevalence of the digestive system symptoms (nausea, emesis, dyspepsia, diarrhea, stomachache, gastro spasm, erosion of angulus oris) in the three study areas was 36.08%, 8.23% and 0.73% successively, and the prevalence of liver and gall diseases was 2.78%, 1.51% and 1.16% successively, and the prevalence of peptic ulcer was 1.14%, 0.50% and 0.29% successively. The more polluted, the higher the prevalence of each digestive system symptoms, liver and gall diseases and peptic ulcer was. Neither of the prevalence of gastrointestinal inflammation and pancreatitis statistically significant correlated to the pollution level. Conclusion Exposure to hexavalent chromium in the environment chronically led to digestive system of the human body damaged.

Key words: hexavalent chromium, pollution, environmental exposure, digestive system, health survey

中图分类号: