Progress on the correlation between circle of Willis and cerebral large and small vessel diseases

doi:10.3969/j.issn.1672-6731.2023.11.003

Abstract

Abstract:

The circle of Willis constitutes the primary collateral circulation of the brain, exerting a significant influence on the distribution of intracranial blood flow. Variations of the circle of Willis can impact the cerebrovascular diseases by diminishing collateral compensation capacity and altering the stability of intracranial hemodynamics. This paper reviews the research progress on the association between circle of Willis and cerebral large vessel disease [such as intracranial arterial dolichoectasia (IADE) and intracranial atherosclerotic stenosis (ICAS)], as well as cerebral small vessel disease (CSVD), so as to provide new ideas for the diagnosis and treatment for these diseases.

Key words: Cerebrovascular disorders, Circle of Willis, Review

摘要：

Willis环构成大脑初级侧支循环，对脑血流分布具有重要影响。Willis环变异通过降低侧支循环代偿功能、改变脑血流动力学稳定性影响脑血管病发生与发展。本文对Willis环变异与脑大血管病（如颅内动脉延长扩张和颅内动脉粥样硬化性狭窄）及小血管病相关性研究进展进行综述，以为疾病的诊断与治疗提供新思路。

关键词: 脑血管障碍, 大脑动脉环, 综述

Lu FENG, Yi-cheng ZHU. Progress on the correlation between circle of Willis and cerebral large and small vessel diseases[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2023, 23(11): 966-971.

冯璐, 朱以诚. Willis环变异与脑大血管病及小血管病相关性研究进展[J]. 中国现代神经疾病杂志, 2023, 23(11): 966-971.

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References 38

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